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Airedale Terrier

18 Airedale Terriers in the atlas. Every number on this page has a source.

18 Airedale Terriers in the Sniff Atlas. Population-genetic snapshot, Mendelian carrier frequencies from Donner 2023, and the data substrate's release version, sample sizes, and evidence tier on every claim.

What the atlas says about Airedale Terrier

In the atlas, the Airedale Terrier clusters consistently as Airedale Terrier (100% of the 18 dogs here). At the trait loci, HMGA2 runs lower than average (6% here vs 56%); RSPO2 runs higher than the atlas average (93% here vs 55%). Dogs here sit in a relatively sparse region of the atlas, fewer close neighbors than typical.

Only 18 dogs of this breed in the atlas, modestly sampled.

Closest genetic neighbors in the atlas: Soft Coated Wheaten Terrier, Rat Terrier, village dog Fiji Kadavu, Yorkshire Terrier, and village dog Fiji Viti Levu.

Genetic dimensions · CanVAS atlas

What the genome says about Airedale Terrier

Computed from the 18,477 research dogs in the Atlas.

Dogs in the Atlas
18Founders
12 from Hayward2016, 3 from Spatola, 2 from JenkinsWGS
Genetic diversity
0.27Tight
Mean heterozygosity across the breed. Too few dogs in this breed (<20) to rank.
Cluster structure
Single tight cluster
Intra-breed RMS distance: 27.17
Nearest genetic relatives
  1. Soft Coated Wheaten Terrier7.04
  2. Rat Terrier7.34
  3. Village Dog Fiji Kadavu7.62
  4. Yorkshire Terrier7.90
  5. Village Dog Fiji Viti Levu8.10
Top-10 PC corrected Euclidean. Lower = closer.
Trait genetics
Allele frequencies at named morphology loci

Frequency of the alternate allele in this breed at each locus's representative SNP.

Body size
IGF120%
HMGA26%
SMAD297%
LCORL97%
STC275%
ADAMTS1734%
Leg length
FGF4·CFA1894%
FGF4·CFA12100%
Coat
RSPO293%
FGF594%
KRT7194%
MC1R97%
Ear set
MSRB3100%
Skull shape
BMP397%
SMOC272%
What you see when you look at a Airedale Terrier

What does the genome say about how a Airedale Terrier looks?

Airedale Terriers look the way they do because of a small set of fixed and near-fixed morphology genes that, taken together, define the visible breed. Each translation below pairs the gene with the trait an owner actually sees, the breed's allele frequency at that locus, and a one-clause causal phrase.

Size and build

IGF1 is at 20% for the small-body allele, leaving the breed firmly in the larger end of the dog body-size spectrum.

HMGA2 is at 6%, leaving most of the size signal to other loci in the panel.

SMAD2 is near-fixed at 97%, a chromosome-7 height locus differentiating small from giant breeds.

LCORL is near-fixed at 97%, the NCAPG/LCORL height locus that is one of the strongest single contributors to canine body size.

STC2 sits at 75%.

ADAMTS17 sits at 34%. ADAMTS17 is a body-size locus also linked to lens disorders.

Leg length

The FGF4 retrogene on chromosome 18 is near-fixed in this breed at 94%. This is the leg-length variant. The breed is fully committed to the long-legged form rather than the short-legged Corgi-and-Dachshund body plan.

The FGF4 retrogene on chromosome 12 is near-fixed at 100%, the chondrodystrophic variant associated with intervertebral disc disease risk in breeds that carry it.

Coat type, length, and color

RSPO2 is near-fixed at 93% for the furnishings allele, the genetic basis of the eyebrows-and-mustache pattern seen in Schnauzers and Wheaten Terriers.

FGF5 is at 94% for the long-coat variant, which is why the breed's coat sits where it does on the long end of the dog coat-length spectrum.

KRT71 is near-fixed at 94% for the wavy/curly variant. Coat curl phenotype varies across breeds at this fixation depending on modifier loci, and visible expression is not always curled even when the locus is fixed.

MC1R is at 97% at the representative SNP. MC1R controls the switch between red-to-gold and black-to-brown pigment, with the e/e homozygous genotype producing the gold-to-red spectrum by blocking eumelanin (black and brown pigment).

Ears

MSRB3 is at 100% for the drop-ear allele, the genetic basis of the breed's signature dropped ear set.

Skull shape

BMP3 is at 97%, contributing to the breed's brachycephalic skull shape.

SMOC2 sits at 72%, contributing to the breed's moderate head shape.

Mendelian-disease genetics

What genetic diseases do Airedale Terriers carry?

From a panel of 250 Mendelian-disease variants screened in 1,054,293 dogs (Donner et al. 2023), Airedale Terriers carry 6 of them at observable frequency. Carrier frequency is not clinical risk. Most recessive variants require two copies for disease expression; many dominant variants show incomplete penetrance. Read this as a population fingerprint of what's in the gene pool, not a per-dog prediction.

Protein Losing Nephropathy (PLN; NPHS1-related)
Autosomal recessive (Incomplete penetrance)
moderate 16.3%
n = 200 dogs · 1 variant tested · OMIA:001326-9615 · omia.org →
Degenerative Myelopathy (DM)
Autosomal recessive (Incomplete penetrance)
moderate 12.8%
n = 200 dogs · 1 variant tested · OMIA:000263-9615 · omia.org →
Hyperuricosuria (HUU)
Autosomal recessive
low 4.0%
n = 200 dogs · 1 variant tested · OMIA:001033-9615 · omia.org →
Cone-Rod Dystrophy (cord1-PRA/crd4)
Autosomal recessive (Incomplete penetrance)
low 3.5%
n = 200 dogs · 1 variant tested · OMIA:001432-9615 · omia.org →
n = 200 dogs · 1 variant tested · OMIA:002251-9615 · omia.org →
Source: Donner J et al. 2023. Frequencies of inherited disease variants in dogs. PLOS Genetics 19(2):e1010651 · Evidence: Limited (DTC ascertainment, tag-SNP proxy) · Confounding MEDIUM · License CC-BY-4.0 · Phene IDs from OMIA (Sydney School of Veterinary Science, The University of Sydney; DOI 10.25910/2AMR-PV70).
Sample size in this breed: 200 dogs from the Donner 2023 cohort.
The data behind this page

Where every number on this page came from.

This page draws on three primary data sources. Carrier frequencies for the Mendelian section come from Donner et al. 2023 (CC-BY-4.0). We grade these data at evidence Limited because the cohort is a direct-to-consumer ascertainment, which biases toward owners who chose to test their dogs. The panel also uses tag-SNP proxies for some variants rather than direct causal-variant assays. Limited is a study-design grade, not a quality grade: the Donner cohort is the largest open canine-genotype dataset in existence and we are grateful for it. We rate the confounding MEDIUM.

Population-genetic dimensions (heterozygosity, intra-breed PCA distance, nearest neighbors, trait-locus frequencies) come from CanVAS (Brundage 2026), harmonized through the Sniff Atlas. The exact release date and verification commit are pinned at the bottom of the page so a researcher can trace a number back to a specific snapshot. The disease-gene-variant graph comes from OMIA (Online Mendelian Inheritance in Animals; Nicholas, Tammen, and the Sydney Informatics Hub at the Sydney School of Veterinary Science, The University of Sydney; retrieved April 2026, DOI 10.25910/2AMR-PV70).

What this page does not yet have. Inheritance modes and per-disease penetrance evidence from Donner 2023 are now in the structured data for every variant the panel covers. Mondo, OMIM, Ensembl, and HGNC cross-references on gene pages remain pending — they arrive in December 2026 alongside the imputed 9.67M-variant CanVAS dataset via the OMIA SQL dump absorption. Until then, gene IDs carry NCBI Gene and OMIA phene URLs only; the wider human-homolog and disease-ontology cross-reference set fills in with that release.

How to cite this page. The computed dimensions on this page are derived from the open Sniff Atlas v1.0.1 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.

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References
  1. Donner J, Anderson H, Davison S, et al. (2023). Frequency and distribution of 152 genetic disease variants in over 1,000,000 mixed-breed and purebred dogs. PLOS Genetics 19(2):e1010651. doi:10.1371/journal.pgen.1010651
  2. Brundage J, et al. (2026). CanVAS: a harmonized canine variant atlas. bioRxiv. doi:10.64898/2026.04.13.718238
  3. Nicholas, F.W., Tammen, I., & Sydney Informatics Hub. (2026). Online Mendelian Inheritance in Animals (OMIA) [dataset]. The University of Sydney. https://omia.org. doi:10.25910/2AMR-PV70 (retrieved April 2026).
Last updated
Sources: CanVAS (Brundage 2026) · Donner 2023 · OMIA