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Canine Mendelian disease records

156 disease records with breed carrier frequencies

Every OMIA-catalogued canine Mendelian disease with carrier-frequency data in the Sniff Atlas. Sorted by number of breeds with observed carriers, so the diseases that segregate most broadly surface first. Frequencies are from the Donner 2023 cohort; penetrance data is included where the Sniff Atlas v1.0.1 has it (45 of 156).

Carrier frequency is variant prevalence at the population level, not disease incidence. Predicted disease relevance at the per-dog level is UNPROVEN; outcome depends on penetrance, modifier loci, and environment. Consult a veterinarian for clinical interpretation.

Severity unclassified
OMIA:000263-9615

Degenerative Myelopathy (DM)

Autosomal recessive (Incomplete penetrance). Observed in 138 of 266 breeds tested — top: Fox Terrier Wire at 82.4%.

Severity unclassified
OMIA:000157-9615

Chondrodystrophy and Intervertebral Disc Disease Risk (CDDY)

Autosomal dominant. Observed in 113 of 266 breeds tested — top: Bavarian Mountain Hound at 100.0%.

High severity
OMIA:000162-9615

Dilated Cardiomyopathy risk factor (Discovered in the Doberman Pinscher; PDK4-related)

Autosomal dominant (Incomplete penetrance). Observed in 97 of 266 breeds tested — top: Lowchen at 75.0%.

Severity unclassified
OMIA:001298-9615

Progressive Rod-Cone Degeneration (prcd-PRA)

Autosomal recessive. Observed in 79 of 266 breeds tested — top: Australian Cattle Dog at 30.7%.

Severity unclassified
OMIA:001432-9615

Cone-Rod Dystrophy (cord1-PRA/crd4)

Autosomal recessive (Incomplete penetrance). Observed in 75 of 266 breeds tested — top: Bulgarian Shepherd at 50.0%.

Severity unclassified
OMIA:001880-9615

Cystinuria Type I-B (SLC7A9 p.A217T)

Autosomal recessive (Incomplete penetrance). Observed in 64 of 266 breeds tested — top: Bulldog Standard at 55.5%.

Severity unclassified
OMIA:001033-9615

Hyperuricosuria (HUU)

Autosomal recessive. Observed in 61 of 266 breeds tested — top: Dalmatian at 92.7%.

Severity unclassified
OMIA:001057-9615

Von Willebrand's Disease, Type 1 (vWD 1)

Autosomal recessive. Observed in 60 of 266 breeds tested — top: Dobermann Pinscher at 36.5%.

Severity unclassified
OMIA:000256-9615

Cystinuria Type I-A (SLC3A1 p.I192V)

Autosomal recessive. Observed in 50 of 266 breeds tested — top: Shikoku Ken at 75.0%.

Severity unclassified
OMIA:000218-9615

Collie Eye Anomaly (CEA)

Autosomal recessive. Observed in 44 of 266 breeds tested — top: Collie at 72.2%.

Severity unclassified
OMIA:000361-9615

Factor VII Deficiency

Autosomal recessive. Observed in 41 of 266 breeds tested — top: Sealyham Terrier at 25.0%.

Severity unclassified
OMIA:000588-9615

Primary Lens Luxation (PLL)

Autosomal recessive. Observed in 38 of 266 breeds tested — top: Volpino Italiano at 23.5%.

Severity unclassified
OMIA:001444-9615

Canine Multifocal Retinopathy 1 (Discovered in Mastiff-related breeds; CMR1)

Autosomal recessive. Observed in 37 of 266 breeds tested — top: Boerboel at 29.7%.

Severity unclassified
OMIA:001466-9615

Exercise-Induced Collapse (EIC)

Autosomal recessive (Incomplete penetrance). Observed in 36 of 266 breeds tested — top: Curly Coated Retriever at 42.9%.

Severity unclassified
OMIA:002168-9615

Bald Thigh Syndrome (Discovered in Sighthounds)

Autosomal recessive. Observed in 32 of 211 breeds tested — top: Borzoi at 100.0%.

Severity unclassified
OMIA:001402-9615

MDR1 (Multidrug Resistance 1) Medication Sensitivity

Autosomal dominant. Observed in 30 of 266 breeds tested — top: Collie at 56.4%.

Severity unclassified
OMIA:002120-9615

Early-Onset Progressive Polyneuropathy (Discovered in the Greyhound)

Autosomal recessive. Observed in 26 of 266 breeds tested — top: Alaskan Malamute at < 1%.

Severity unclassified
OMIA:001514-9615

Acral Mutilation Syndrome (AMS)

Autosomal recessive. Observed in 22 of 266 breeds tested — top: Cirneco Del Etna at 14.3%.

Severity unclassified
OMIA:000247-9615

Pituitary-Dependent Hyperadrenocorticism (Discovered in Poodles)

Autosomal dominant. Observed in 22 of 266 breeds tested — top: Bracco Italiano at 12.5%.

Severity unclassified
OMIA:002244-9615

Craniomandibular Osteopathy (Discovered in the Cairn, Scottish and West Highland White Terrier)

Autosomal dominant (Incomplete penetrance). Observed in 18 of 266 breeds tested — top: West Highland White Terrier at 24.5%.

Severity unclassified
OMIA:002198-9615

Progressive Retinal Atrophy (Discovered in the Giant Schnauzer; NECAP1-related)

Autosomal recessive. Observed in 18 of 266 breeds tested — top: Dachshund Shorthaired at 25.0%.

Severity unclassified
OMIA:001588-9615

Ichthyosis (Discovered in the Golden Retriever)

Autosomal recessive. Observed in 17 of 266 breeds tested — top: Golden Retriever at 27.5%.

Severity unclassified
OMIA:001138-9615

Hypocatalasia

Autosomal recessive. Observed in 16 of 266 breeds tested — top: American Foxhound at 14.8%.

Severity unclassified
OMIA:002434-9615

Macrothrombocytopenia (Discovered in the Norfolk and Cairn Terrier)

Autosomal recessive. Observed in 16 of 266 breeds tested — top: Norfolk Terrier at 47.1%.

Severity unclassified
OMIA:002179-9615

Stargardt Disease (Discovered in the Labrador Retriever)

Autosomal recessive. Observed in 13 of 266 breeds tested — top: Labrador Retriever at 11.2%.

Severity unclassified
OMIA:001805-9615

Amelogenesis Imperfecta (Discovered in the Parson Russell Terrier; AI)

Autosomal recessive. Observed in 12 of 266 breeds tested — top: Italian Greyhound at 22.6%.

Severity unclassified
OMIA:000819-9615

Prekallikrein Deficiency

Autosomal recessive. Observed in 12 of 266 breeds tested — top: Shih Tzu at 10.5%.

Severity unclassified
OMIA:001772-9615

Skeletal Dysplasia 2 (SD2)

Autosomal recessive. Observed in 12 of 266 breeds tested — top: Sussex Spaniel at 100.0%.

Severity unclassified
OMIA:002015-9615

Dental Hypomineralisation (Discovered in the Border Collie)

Autosomal recessive. Observed in 11 of 266 breeds tested — top: Border Collie at 1.1%.

Severity unclassified
OMIA:001970-9615

Polyneuropathy with Ocular Abnormalities and Neuronal Vacuolation (Discovered in the Black Russian Terrier and Rottweiler; POANV)

Autosomal recessive. Observed in 11 of 266 breeds tested — top: Black Russian Terrier at 8.7%.

Severity unclassified
OMIA:001353-9615

Canine Scott Syndrome (CSS)

Autosomal recessive. Observed in 10 of 266 breeds tested — top: Presa Canario at 1.6%.

Severity unclassified
OMIA:002365-9615

Dilated Cardiomyopathy (Discovered in the Schnauzer; DCM)

Autosomal recessive. Observed in 10 of 266 breeds tested — top: Schnauzer Standard at 3.3%.

Severity unclassified
OMIA:001326-9615

Protein Losing Nephropathy (PLN; NPHS1-related)

Autosomal recessive (Incomplete penetrance). Observed in 10 of 266 breeds tested — top: Soft Coated Wheaten Terrier at 18.0%.

Severity unclassified
OMIA:001561-9615

Shar-Pei Autoinflammatory Disease (SPAID)

Autosomal dominant (Incomplete penetrance). Observed in 10 of 266 breeds tested — top: Chinese Shar Pei at 67.0%.

Severity unclassified
OMIA:001564-9615

Bleeding disorder (Discovered in the Greater Swiss Mountain Dog; P2RY12-related)

Autosomal recessive. Observed in 9 of 266 breeds tested — top: Greater Swiss Mountain Dog at 21.2%.

Severity unclassified
OMIA:000685-9615

Congenital Myasthenic Syndrome (Discovered in the Heideterrier; CHRNE-related; CMS)

Autosomal recessive. Observed in 9 of 266 breeds tested — top: Fox Terrier Smooth at 12.5%.

Severity unclassified
OMIA:002203-9615

Ehlers-Danlos Syndrome (Discovered in the Chihuahua and Poodle)

Autosomal recessive. Observed in 9 of 211 breeds tested — top: Miniature Pinscher at 50.0%.

Severity unclassified
OMIA:001400-9615

Osteochondrodysplasia (Discovered in the Miniature Poodle)

Autosomal recessive. Observed in 9 of 266 breeds tested — top: Papillon at 4.6%.

Severity unclassified
OMIA:001886-9615

Chondrodysplasia, Disproportionate Short-limbed (Discovered in the Norwegian Elkhound; ITGA10-related)

Autosomal recessive. Observed in 8 of 266 breeds tested — top: Chinook at 14.0%.

Severity unclassified
OMIA:001879-9615

Cystinuria Type II-A (Discovered in the Australian Cattle Dog)

Autosomal dominant. Observed in 8 of 266 breeds tested — top: Australian Cattle Dog at 2.3%.

Severity unclassified
OMIA:001786-9615

Intestinal Cobalamin Malabsorption (Discovered in the Border Collie; CUBN-related)

Autosomal recessive. Observed in 8 of 266 breeds tested — top: Komondor at 17.9%.

Severity unclassified
OMIA:001503-9615

Neuronal Ceroid Lipofuscinosis 4A (Discovered in the American Staffordshire Terrier; NCL4A)

Autosomal recessive. Observed in 8 of 266 breeds tested — top: American Staffordshire Terrier at 3.4%.

Severity unclassified
OMIA:001374-9615

Centronuclear Myopathy (Discovered in the Labrador Retriever; HACD1-related; CNM)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Labrador Retriever at 1.0%.

Severity unclassified
OMIA:001327-9615

Hereditary Footpad Hyperkeratosis (Discovered in the Irish Terrier and Kromfohrländer)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Bedlington Terrier at 13.6%.

Severity unclassified
OMIA:001509-9615

Musladin-Lueke syndrome (MLS)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Beagle at 1.7%.

Severity unclassified
OMIA:002152-9615

Neuroaxonal Dystrophy (Discovered in the Rottweiler; VPS11-related)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Rottweiler at 3.0%.

Severity unclassified
OMIA:001984-9615

Progressive Retinal Atrophy (Discovered in the Golden Retriever; GR_PRA2)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Golden Retriever at 2.8%.

Severity unclassified
OMIA:001932-9615

Progressive Retinal Atrophy (Discovered in the Swedish Vallhund; MERTK-related)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Swedish Vallhund at 43.8%.

Severity unclassified
OMIA:002089-9615

Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10-related; SCA)

Autosomal recessive. Observed in 7 of 266 breeds tested — top: Fox Terrier Toy at 3.1%.

Severity unclassified
OMIA:002174-9615

Congenital Dyshormonogenic Hypothyroidism with Goiter (Discovered in the Shih Tzu)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Pekingese at 1.0%.

Severity unclassified
OMIA:000536-9615

Congenital Hypothyroidism (Discovered in the Toy Fox and Rat Terrier)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Fox Terrier Toy at 4.2%.

Severity unclassified
OMIA:002148-9615

Deafness and Vestibular Dysfunction (Discovered in the Doberman Pinscher)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Mudi at 4.8%.

Severity unclassified
OMIA:001373-9615

Hereditary Nasal Parakeratosis (Discovered in the Labrador Retriever; HNPK)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Saluki at 4.2%.

Severity unclassified
OMIA:001506-9615

Neuronal Ceroid Lipofuscinosis 8 (Discovered in the Australian Shepherd; NCL8)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Gordon Setter at 5.0%.

Severity unclassified
OMIA:000791-9615

Persistent Müllerian Duct Syndrome (PMDS)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Schnauzer Miniature at 9.4%.

Severity unclassified
OMIA:001572-9615

Progressive Retinal Atrophy (Discovered in the Golden Retriever; GR_PRA1)

Autosomal recessive. Observed in 6 of 266 breeds tested — top: Golden Retriever at 1.6%.

Severity unclassified
OMIA:002539-9615

Acute Respiratory Distress Syndrome (Discovered in the Dalmatian; ARDS)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Bloodhound at < 1%.

Severity unclassified
OMIA:001365-9615

Cone Degeneration (Discovered in the Alaskan Malamute)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Alaskan Malamute at < 1%.

Severity unclassified
OMIA:001592-9615

Episodic Falling (EF)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Cavalier King Charles Spaniel at 6.7%.

Severity unclassified
OMIA:000366-9615

Fanconi Syndrome

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Basenji at 11.2%.

Severity unclassified
OMIA:000421-9615

Glycogen storage disease VII (GSD VII) or Phosphofructokinase (PFK) Deficiency

Autosomal recessive. Observed in 5 of 266 breeds tested — top: English Springer Spaniel at 1.9%.

Severity unclassified
OMIA:001980-9615

Ichthyosis (Discovered in the American Bulldog; NIPAL4-related)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Bulldog American at 9.1%.

Severity unclassified
OMIA:001482-9615

Neuronal Ceroid Lipofuscinosis 5 (Discovered in the Border Collie; NCL5)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Australian Cattle Dog at 1.5%.

Severity unclassified
OMIA:001977-9615

Progressive Retinal Atrophy (Discovered in the Shetland Sheepdog; CNGA1-PRA)

Autosomal recessive. Observed in 5 of 265 breeds tested — top: Shetland Sheepdog at < 1%.

Severity unclassified
OMIA:000844-9615

Pyruvate Kinase (PK) Deficiency (Discovered in the Beagle)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Beagle at < 1%.

Severity unclassified
OMIA:001669-9615

Rod-Cone Dysplasia 1a (Discovered in the Sloughi; rcd1a)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Kooikerhondje at < 1%.

Severity unclassified
OMIA:001314-9615

Rod-Cone Dysplasia 3 (Discovered in the Cardigan Welsh Corgi; rcd3)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Chinese Crested at 1.5%.

Severity unclassified
OMIA:002016-9615

Van den Ende-Gupta Syndrome (VDEGS)

Autosomal recessive. Observed in 5 of 266 breeds tested — top: Fox Terrier Wire at 20.8%.

Severity unclassified
OMIA:000155-9615

Complement 3 (C3) Deficiency

Autosomal recessive. Observed in 4 of 266 breeds tested — top: Brittany at < 1%.

Severity unclassified
OMIA:000710-9615

Familial Nephropathy (Discovered in the English Cocker Spaniel; FN)

Autosomal recessive. Observed in 4 of 266 breeds tested — top: Welsh Springer Spaniel at 4.2%.

Severity unclassified
OMIA:000703-9615

Narcolepsy (Discovered in the Labrador Retriever)

Autosomal recessive. Observed in 4 of 266 breeds tested — top: Labrador Retriever at < 1%.

Severity unclassified
OMIA:001552-9615

Neuronal Ceroid Lipofuscinosis 12 (Discovered in the Australian Cattle Dog)

Autosomal recessive. Observed in 4 of 265 breeds tested — top: Australian Cattle Dog at 1.2%.

Severity unclassified
OMIA:002433-9615

Thrombopathia (Discovered in the Eskimo Spitz)

Autosomal recessive. Observed in 4 of 266 breeds tested — top: Basset Hound at 1.3%.

Severity unclassified
OMIA:001819-9615

Xanthinuria, Type II (Discovered in the Cavalier King Charles Spaniel)

Autosomal recessive. Observed in 4 of 266 breeds tested — top: Manchester Terrier Toy at 4.2%.

Severity unclassified
OMIA:002484-9615

Bardet-Biedl syndrome 2 or Progressive Retinal Atrophy (Discovered in the Shetland Sheepdog; BBS2-PRA)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Shetland Sheepdog at 2.1%.

Severity unclassified
OMIA:001913-9615

Cerebellar Ataxia (Discovered in the Old English Sheepdog and the Gordon Setter)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Old English Sheepdog at 3.8%.

Severity unclassified
OMIA:002196-9615

Deafness and Vestibular Dysfunction (Discovered in the Doberman Pinscher; PTPRQ-related)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Dobermann Pinscher at < 1%.

Severity unclassified
OMIA:000341-9615

Dystrophic Epidermolysis Bullosa (Discovered in the Golden Retriever)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Rhodesian Ridgeback at < 1%.

Severity unclassified
OMIA:002088-9615

Focal Non-Epidermolytic Palmoplantar Keratoderma (Discovered in the Dogue de Bordeaux)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Dogue De Bordeaux at 1.5%.

Severity unclassified
OMIA:000578-9615

Globoid Cell Leukodystrophy (Discovered in Terriers)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Cairn Terrier at < 1%.

Severity unclassified
OMIA:002151-9615

Microphthalmia (Discovered in the Soft-Coated Wheaten Terrier)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Russell Terrier at 6.5%.

Severity unclassified
OMIA:000667-9615

Mucopolysaccharidosis, Type VII (Discovered in the German Shepherd Dog; MPS VII)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Terrier Brazileiro at 10.0%.

Severity unclassified
OMIA:001967-9615

Muscular Dystrophy, Ullrich Type (Discovered in the Landseer)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Landseer at 25.0%.

Severity unclassified
OMIA:001523-9615

Oculoskeletal Dysplasia (OSD2)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Samoyed at 1.2%.

Severity unclassified
OMIA:001976-9615

Primary Open Angle Glaucoma (Discovered in Basset Fauve de Bretagne; ADAMTS17-related; POAG)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Basset Griffon Vendeen Petit at 25.0%.

Severity unclassified
OMIA:001870-9615

Primary Open Angle Glaucoma (Discovered in the Beagle; POAG)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Laika at 8.3%.

Severity unclassified
OMIA:002320-9615

Progressive Retinal Atrophy (Discovered in the Lapponian Herder; IFT122-PRA)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Lapponian Herder at 15.4%.

Severity unclassified
OMIA:002289-9615

Progressive Retinal Atrophy (Discovered in the Lhasa Apso; IMPG2-related PRA4)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Lhasa Apso at < 1%.

Severity unclassified
OMIA:000882-9615

Rod-Cone Dysplasia 1 (Discovered in the Irish Setter; rcd1)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Irish Setter at 1.2%.

Severity unclassified
OMIA:002032-9615

Sensory Neuropathy (Discovered in the Border Collie)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Border Collie at < 1%.

Severity unclassified
OMIA:002110-9615

Spongy Degeneration with Cerebellar Ataxia (Discovered in the Belgian Malinois; ATP1B2-related SDCA2)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Belgian Malinois at 4.4%.

Severity unclassified
OMIA:001058-9615

Von Willebrand's Disease, Type 3 (Discovered in the Shetland Sheepdog; vWD 3)

Autosomal recessive. Observed in 3 of 266 breeds tested — top: Scottish Terrier at 1.3%.

Severity unclassified
OMIA:000078-9615

Bandera's Neonatal Ataxia (BNAt)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Coton De Tulear at 2.4%.

Severity unclassified
OMIA:001553-9615

Canine Multifocal Retinopathy 2 (Discovered in the Coton de Tulear; CMR2)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Coton De Tulear at 4.8%.

Severity unclassified
OMIA:001554-9615

Canine Multifocal Retinopathy 3 (Discovered in the Lapponian Herder; CMR3)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Lapponian Herder at 13.5%.

Severity unclassified
OMIA:001674-9615

Cone-Rod Dystrophy 1 (Discovered in the American Staffordshire Terrier; crd1)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: American Staffordshire Terrier at 1.0%.

Severity unclassified
OMIA:001675-9615

Cone-Rod Dystrophy 2 (Discovered in the Pit Bull Terrier; crd2)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: American Staffordshire Terrier at < 1%.

Severity unclassified
OMIA:001928-9615

Congenital Myasthenic Syndrome (Discovered in the Labrador Retriever)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Labrador Retriever at < 1%.

Severity unclassified
OMIA:001000-9615

Glanzmann Thrombasthenia, Type I (Discovered in the Great Pyrenees)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Great Pyrenees at < 1%.

Severity unclassified
OMIA:000418-9615

Glycogen Storage Disease, Type Ia (GSD Ia)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Maltese at < 1%.

Severity unclassified
OMIA:000402-9615

GM1 Gangliosidosis (Discovered in the Shiba)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Portuguese Water Dog at < 1%.

Severity unclassified
OMIA:001318-9615

Hereditary Elliptocytosis

Autosomal dominant. Observed in 2 of 266 breeds tested — top: Golden Retriever at < 1%.

Severity unclassified
OMIA:000526-9615

Hypomyelination (Discovered in the Weimaraner)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Weimaraner at < 1%.

Severity unclassified
OMIA:002146-9615

Lethal Acrodermatitis (Discovered in the Bull Terrier; LAD)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Bull Terrier Standard at 7.4%.

Severity unclassified
OMIA:002251-9615

Lung Developmental Disease (Discovered in the Airedale Terrier)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Airedale Terrier at 2.8%.

Severity unclassified
OMIA:002028-9615

Myeloperoxidase Deficiency (Discovered in the Italian Hound)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Beagle at < 1%.

Severity unclassified
OMIA:000698-9615

Myotonia Congenita (Discovered in the Australian Cattle Dog)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Border Collie at < 1%.

Severity unclassified
OMIA:002092-9615

Neonatal Cerebellar Cortical Degeneration (SPTBN2-related; NCCD)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Beagle at < 1%.

Severity unclassified
OMIA:001962-9615

Neuronal Ceroid Lipofuscinosis 7 (Discovered in the Chinese Crested Dog and Chihuahua; NCL7)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Chihuahua at < 1%.

Severity unclassified
OMIA:002336-9615

Nonsyndromic hearing loss (Discovered in the Rottweiler)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Rottweiler at < 1%.

Severity unclassified
OMIA:001483-9615

Osteogenesis Imperfecta (Discovered in the Dachshund; OI)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Dachshund Miniature Shorthaired at < 1%.

Severity unclassified
OMIA:002315-9615

Pituitary Dwarfism (Discovered in the Karelian Bear Dog; POU1F1-related)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Karelian Bear Dog at 4.4%.

Severity unclassified
OMIA:000807-9615

Polycystic Kidney Disease (Discovered in the Bull Terrier)

Autosomal dominant. Observed in 2 of 266 breeds tested — top: Labrador Retriever at < 1%.

Severity unclassified
OMIA:002206-9615

Primary Ciliary Dyskinesia (Discovered in the Alaskan Malamute; NME5-related; PCD)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Alaskan Malamute at 1.4%.

Severity unclassified
OMIA:001540-9615

Primary Ciliary Dyskinesia (Discovered in the Old English Sheepdog; CCDC39-related PCD)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Old English Sheepdog at 1.4%.

Severity unclassified
OMIA:000830-9615

Progressive Retinal Atrophy (Discovered in the Papillon and Phalène; CNGB1-related; PAP1_PRA)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Brussels Griffon at 1.7%.

Severity unclassified
OMIA:001428-9615

Trapped Neutrophil Syndrome (TNS)

Autosomal recessive. Observed in 2 of 266 breeds tested — top: Border Collie at 2.8%.

Severity unclassified
OMIA:001596-9615

Benign Familial Juvenile Epilepsy (Discovered in the Lagotto Romagnolo; BFJE)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Lagotto Romagnolo at 12.7%.

Severity unclassified
OMIA:001525-9615

Canine Leukocyte Adhesion Deficiency (CLAD), Type III

Autosomal recessive. Observed in 1 of 266 breeds tested — top: German Shepherd at < 1%.

Severity unclassified
OMIA:001468-9615

Canine Multiple Systems Degeneration (Discovered in the Chinese Crested Dog; CMSD)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Chinese Crested at < 1%.

Severity unclassified
OMIA:001660-9615

Centronuclear Myopathy (Discovered in the Great Dane; BIN1-related; CNM)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Great Dane at < 1%.

Severity unclassified
OMIA:001140-9615

Cleft Lip with/without Palate and Syndactyly (ADAMTS20-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Nova Scotia Duck Tolling Retriever at 4.8%.

Severity unclassified
OMIA:001919-9615

Cleft Palate (DLX6-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Nova Scotia Duck Tolling Retriever at < 1%.

Severity unclassified
OMIA:002117-9615

Congenital Cornification Disorder (Discovered in the Chihuahua)

X-linked semi-dominant. Observed in 1 of 211 breeds tested — top: Azawakh at 11.5%.

Severity unclassified
OMIA:000236-9615

Craniomandibular Osteopathy (Discovered in the Weimaraner; CMO)

Autosomal dominant. Observed in 1 of 211 breeds tested — top: Weimaraner at 16.1%.

Severity unclassified
OMIA:001947-9615

Dandy-Walker-Like Malformation (Discovered in the Eurasier; DWLM)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Eurasier at 10.5%.

Severity unclassified
OMIA:002284-9615

Demyelinating Polyneuropathy (Discovered in the Miniature Schnauzer; SBF2-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Schnauzer Miniature at < 1%.

Severity unclassified
OMIA:001346-9615

Dominant Progressive Retinal Atrophy (DPRA)

Autosomal dominant. Observed in 1 of 266 breeds tested — top: Mastiff at < 1%.

Severity unclassified
OMIA:001521-9615

Early-onset PRA (Discovered in the Portuguese Water Dog; EOPRA)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Portuguese Water Dog at < 1%.

Severity unclassified
OMIA:001577-9615

Glycogen Storage Disease, Type IIIa (GSD IIIa)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Curly Coated Retriever at 6.3%.

Severity unclassified
OMIA:001461-9615

GM2 Gangliosidosis (Discovered in the Japanese Chin)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Japanese Chin at 3.2%.

Severity unclassified
OMIA:000437-9615

Hemophilia A (Discovered in the German Shepherd Dog; F8 p.C548Y)

X-linked recessive. Observed in 1 of 266 breeds tested — top: German Shepherd at < 1%.

Severity unclassified
OMIA:002279-9615

Hereditary Ataxia (Discovered the in Belgian Malinois; SLC12A6-related)

Autosomal recessive. Observed in 1 of 211 breeds tested — top: Belgian Malinois at < 1%.

Severity unclassified
OMIA:001431-9615

Hereditary Vitamin D-Resistant Rickets Type II

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Pomeranian at < 1%.

Severity unclassified
OMIA:002162-9615

Hypophosphatasia (Discovered in the Karelian Bear Dog; ALPL-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Karelian Bear Dog at 11.0%.

Severity unclassified
OMIA:001973-9615

Ichthyosis (Discovered in the Great Dane; SLC27A4-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Great Dane at < 1%.

Severity unclassified
OMIA:002324-9615

Juvenile Encephalopathy (Discovered in the Parson Russell Terrier)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Parson Russell Terrier at 2.2%.

Severity unclassified
OMIA:002095-9615

Juvenile Myoclonic Epilepsy (Discovered in the Rhodesian Ridgeback; JME)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Rhodesian Ridgeback at 1.1%.

Severity unclassified
OMIA:001371-9615

L-2-Hydroxyglutaric Aciduria (Discovered in the Staffordshire Bull Terrier)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Staffordshire Bull Terrier at 1.5%.

Severity unclassified
OMIA:001954-9615

Lagotto Storage Disease (LSD)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Lagotto Romagnolo at 1.9%.

Severity unclassified
OMIA:000546-9615

Lamellar Ichthyosis (LI)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Shih Tzu at < 1%.

Severity unclassified
OMIA:002119-9615

Leonberger Polyneuropathy, Type 2 (LPN2)

Autosomal dominant (Incomplete penetrance). Observed in 1 of 266 breeds tested — top: Dachshund Miniature Shorthaired at < 1%.

Severity unclassified
OMIA:002122-9615

Limb-girdle Muscular Dystrophy, Type 2F (Discovered in the Boston Terrier)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Boston Terrier at < 1%.

Severity unclassified
OMIA:001081-9615

Muscular Dystrophy (Discovered in the Golden Retriever)

X-linked recessive. Observed in 1 of 266 breeds tested — top: Golden Retriever at < 1%.

Severity unclassified
OMIA:000683-9615

Muscular Hypertrophy (Double Muscling)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Greyhound at < 1%.

Severity unclassified
OMIA:001471-9615

Neonatal Encephalopathy with Seizures (NEWS)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Poodle Standard at < 1%.

Severity unclassified
OMIA:002105-9615

Neuroaxonal Dystrophy (Discovered in the Papillon; PLA2G6-related; NAD)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Papillon at < 1%.

Severity unclassified
OMIA:001975-9615

Neuroaxonal Dystrophy (Discovered in the Spanish Water Dog; NAD)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Lagotto Romagnolo at < 1%.

Severity unclassified
OMIA:002084-9615

Paroxysmal Dyskinesia (Discovered in the Irish Soft Coated Wheaten Terrier; PIGN-related; PxD)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Soft Coated Wheaten Terrier at 3.1%.

Severity unclassified
OMIA:001692-9615

Progressive Early-Onset Cerebellar Ataxia (Discovered in the Finnish Hound; SEL1L-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Finnish Hound at 5.6%.

Severity unclassified
OMIA:001876-9615

Progressive Retinal Atrophy (Discovered in the Basenji; SAG-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Basenji at 10.7%.

Severity unclassified
OMIA:001918-9615

Progressive Retinal Atrophy, Type III (Discovered in the Tibetan Spaniel and Tibetan Terrier; PRA type III; FAM161A-related)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Tibetan Spaniel at 1.4%.

Severity unclassified
OMIA:001335-9615

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)

Autosomal dominant. Observed in 1 of 266 breeds tested — top: German Shepherd at < 1%.

Severity unclassified
OMIA:001820-9615

Spinocerebellar Ataxia (Late-Onset Ataxia; CAPN1-related; SCA/LOA)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: Parson Russell Terrier at 6.4%.

Severity unclassified
OMIA:001339-9615

Von Willebrand's Disease, Type 2 (vWD 2)

Autosomal recessive. Observed in 1 of 266 breeds tested — top: German Shorthaired Pointer at < 1%.

Severity unclassified
OMIA:000831-9615

X-Linked Progressive Retinal Atrophy 1 (XLPRA1)

X-linked recessive. Observed in 1 of 266 breeds tested — top: Siberian Husky at < 1%.