Toy Fox Terrier
8 Toy Fox Terriers in the atlas. Every number on this page has a source.
8 Toy Fox Terriers in the Sniff Atlas. Population-genetic snapshot, Mendelian carrier frequencies from Donner 2023, and the data substrate's release version, sample sizes, and evidence tier on every claim.
In the atlas, the Toy Fox Terrier clusters consistently as Toy Fox Terrier (100% of the 8 dogs here). At the trait loci, SMAD2 runs lower than average (0% here vs 74%); HMGA2 runs lower than average (0% here vs 56%).
Low breed predictability score (0.15), individual dogs of this breed vary widely in genetics, suggesting active substructure or sub-population diversity. Only 8 dogs of this breed in the atlas, every individual contributes outsized weight to the breed's computed profile.
Closest genetic neighbors in the atlas: American Hairless Terrier, Irish Terrier, Silky Terrier, American Eskimo Dog, and Australian Terrier.
What the genome says about Toy Fox Terrier
Computed from the 18,477 research dogs in the Atlas.
- American Hairless Terrier4.44
- Irish Terrier4.63
- Silky Terrier5.05
- American Eskimo Dog5.93
- Australian Terrier6.37
Frequency of the alternate allele in this breed at each locus's representative SNP.
| IGF1 | 50% |
| HMGA2 | 0% |
| SMAD2 | 0% |
| LCORL | 75% |
| STC2 | 50% |
| ADAMTS17 | 50% |
| FGF4·CFA18 | 63% |
| FGF4·CFA12 | 100% |
| RSPO2 | 50% |
| FGF5 | 38% |
| KRT71 | 100% |
| MC1R | 75% |
| MSRB3 | 50% |
| BMP3 | 50% |
| SMOC2 | 100% |
What does the genome say about how a Toy Fox Terrier looks?
Toy Fox Terriers look the way they do because of a small set of fixed and near-fixed morphology genes that, taken together, define the visible breed. Each translation below pairs the gene with the trait an owner actually sees, the breed's allele frequency at that locus, and a one-clause causal phrase.
Size and build
IGF1 sits at 50% for the small-body allele. IGF1 is the gene that sets dog body size from Chihuahua to Great Dane. Intermediate frequencies typically keep a breed in the mid-sized range rather than tipping toward the larger working forms.
HMGA2 is at 0%, leaving most of the size signal to other loci in the panel.
SMAD2 is at 0%, leaving the height signal mostly to other size genes.
LCORL sits at 75% at the NCAPG/LCORL height locus on chromosome 3.
STC2 sits at 50%.
ADAMTS17 sits at 50%. ADAMTS17 is a body-size locus also linked to lens disorders.
Leg length
The FGF4 retrogene on chromosome 18 sits at 63%. This is the leg-length variant. The intermediate frequency means some dogs in this breed carry the short-legged allele and some do not.
The FGF4 retrogene on chromosome 12 is near-fixed at 100%, the chondrodystrophic variant associated with intervertebral disc disease risk in breeds that carry it.
Coat type, length, and color
RSPO2 sits at 50% for the furnishings variant. Furnishings (the eyebrow-and-mustache pattern seen in Schnauzers and Wheaten Terriers) vary across the population at this intermediate frequency, and visible expression depends on the specific allele combination each dog carries.
FGF5 sits at 38% for the long-coat variant. Coat length is influenced by other loci as well, so intermediate FGF5 frequencies do not always correspond to intermediate visible coat lengths.
KRT71 is near-fixed at 100% for the wavy/curly variant. Coat curl phenotype varies across breeds at this fixation depending on modifier loci, and visible expression is not always curled even when the locus is fixed.
MC1R sits at 75% at the representative SNP. MC1R controls the switch between red-to-gold pigment and black-to-brown pigment, with the e/e homozygous genotype producing the gold-to-red spectrum. Substrate frequencies at this SNP depend on the array's polarity, so visible coat color in the breed is a more reliable indicator than this single number.
Ears
MSRB3 sits at 50% for the drop-ear allele, which is why ear set varies across the breed.
Skull shape
BMP3 sits at 50%, contributing to the breed's moderate, mesaticephalic head shape rather than the extreme brachycephalic form.
SMOC2 is at 100%, the major locus contributing to the breed's brachycephalic face shape.
Where every number on this page came from.
This page draws on three primary data sources. Carrier frequencies for the Mendelian section come from Donner et al. 2023 (CC-BY-4.0). We grade these data at evidence Limited because the cohort is a direct-to-consumer ascertainment, which biases toward owners who chose to test their dogs. The panel also uses tag-SNP proxies for some variants rather than direct causal-variant assays. Limited is a study-design grade, not a quality grade: the Donner cohort is the largest open canine-genotype dataset in existence and we are grateful for it. We rate the confounding MEDIUM.
Population-genetic dimensions (heterozygosity, intra-breed PCA distance, nearest neighbors, trait-locus frequencies) come from CanVAS (Brundage 2026), harmonized through the Sniff Atlas. The exact release date and verification commit are pinned at the bottom of the page so a researcher can trace a number back to a specific snapshot. The disease-gene-variant graph comes from OMIA (Online Mendelian Inheritance in Animals; Nicholas, Tammen, and the Sydney Informatics Hub at the Sydney School of Veterinary Science, The University of Sydney; retrieved April 2026, DOI 10.25910/2AMR-PV70).
What this page does not yet have. Inheritance modes and per-disease penetrance evidence from Donner 2023 are now in the structured data for every variant the panel covers. Mondo, OMIM, Ensembl, and HGNC cross-references on gene pages remain pending — they arrive in December 2026 alongside the imputed 9.67M-variant CanVAS dataset via the OMIA SQL dump absorption. Until then, gene IDs carry NCBI Gene and OMIA phene URLs only; the wider human-homolog and disease-ontology cross-reference set fills in with that release.
How to cite this page. The computed dimensions on this page are derived from the open Sniff Atlas v1.0.1 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.
We have 8 toy fox terriers. We do not have yours.
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- Donner J, Anderson H, Davison S, et al. (2023). Frequency and distribution of 152 genetic disease variants in over 1,000,000 mixed-breed and purebred dogs. PLOS Genetics 19(2):e1010651. doi:10.1371/journal.pgen.1010651
- Brundage J, et al. (2026). CanVAS: a harmonized canine variant atlas. bioRxiv. doi:10.64898/2026.04.13.718238
- Nicholas, F.W., Tammen, I., & Sydney Informatics Hub. (2026). Online Mendelian Inheritance in Animals (OMIA) [dataset]. The University of Sydney. https://omia.org. doi:10.25910/2AMR-PV70 (retrieved April 2026).