RPGR
RPGR is a gene catalogued in the canine genome. Below are the inherited conditions OMIA links to it in dogs, its human counterpart, and its canonical records across the genomics world.
The inherited conditions OMIA associates with RPGR in dogs. Each links to the full record.
RPGR as it is catalogued across the genomics world. Each link is the canonical record, so this gene composes with everything those resources know.
- NCBI Gene 403726
- Ensembl ENSCAFG00000014003
- RefSeq NP_001003126.1
- OMIA disease OMIA:000831-9615
- OMIA disease OMIA:001518-9615
In humans, this gene's counterpart is RPGR. That ortholog is what connects RPGR to a century of human medical genetics. The dog and human proteins are 47% identical (a lower-confidence 1:1 call, shown for transparency, not hidden).
In people, variants in the RPGR gene are classified as pathogenic in ClinVar for 8 expert-reviewed conditions.
Dog and human evidence are symmetric here, a validated cross-species footprint. Coverage, not importance. D = 1 dog vs H = 1 human cited disease channels.
Lookup and discovery are candidate-framed research surfaces. Classification renders AVCG grades we cite; Sniff does not score variants with a model of its own.
Per-breed allele frequencies across the atlas are surfaced for the trait loci Sniff has verified a direction-of-effect for. For RPGR we show the cited identity and disease associations, and we would rather show you exactly that than a frequency we cannot yet interpret honestly. See the gene catalog for trait loci with frequency views and every disease-linked gene page.
Gene identity and disease associations are grounded in OMIA (CC-BY) and the open Sniff Atlas. Full citation formats at sniff.world/cite.