Skip to main content
snıff

Reverse query / human → dog

MONDO:0009710.

Which dogs are a natural model of this human disease. Each row is a distinct gene pathway with a canine model, ranked by evidence strength. We assert the canine disease models the human one (gene-level), never that a dog allele equals a human variant.

2 model pathways 2 OMIA-anchored MONDO:0009710 ↗
Evidence
Canine model pathway Evidence Ortholog Human anchor Canine variant · assembly
CLCN1 → CLCN1 OMIA model-of OMIA-anchored one_to_one — gene-level (no single variant)
— OMIA model-of OMIA-anchored one2one — gene-level (no single variant)
The boundary of this model. The rows above are the characterized pathways, human genes of this disease with a canine model in our substrate. We do not hold a GenCC established-gene panel for this specific Mondo id, so the full gene landscape is not enumerated here; we show the canine models we hold and do not imply full coverage.
A candidate model is a computational hypothesis (gene-level model-of, INV-57), never a confirmed model; confirmation is DNA plus phenotype, in the lab. Canine coordinates are on UU_Cfam_GSD_1.0 and carry their assembly (no cross-assembly comparison without a scored liftover). Sources: OMIA, ClinVar (Landrum 2018), Ensembl Compara orthology, Mondo. Ranked by evidence strength within this human disease.